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Iowa State Cyclones vs Arizona Wildcats prediction

College football · Saturday, October 24, 2026 · 7:30 PM ET · Casino Del Sol Stadium · ESPN2

Result

Final: Iowa State Cyclones 3, Arizona Wildcats 39 (Arizona Wildcats won). Mel’s pick (Arizona Wildcats win 84% of the time) was right.

Mel’s pick

Arizona Wildcats win 84% of the time in Mel’s Playbook’s default simulation of this game, saved before it started.

Projected score

Iowa State Cyclones 20, Arizona Wildcats 33. 16% of the simulations finished as one-score games.

Mel vs the betting line

Mel’s margin (Arizona Wildcats by about 13) is close to the line (Arizona Wildcats −12.5), so there’s no real lean against the spread.

The total is 51.5; Mel’s projected 52.7 is right around it.

Recent form

Iowa State Cyclones (3-3) scored 28 and allowed 24 points a game over their last 5.

Arizona Wildcats (5-1) scored 35.8 and allowed 21.4 points a game over their last 5.

Based on this season’s stats, injuries, rest, travel and the betting market. Updated Oct 24, 5:58 PM ET.

See the full simulation

Mel’s Playbook Pro shows the range of likely totals and margins, player props and every factor behind the pick, and lets you tune the model (home field, injuries, momentum and more) and re-run the game.

Open in Mel’s Playbook Try the free demo game

Every default-model prediction is saved before the game and graded against the final score on our public results page. Simulations are estimates, not guarantees, and this is not betting advice. 21+ where applicable; if gambling is a problem, call 1-800-GAMBLER.