Cleveland Cavaliers vs Philadelphia 76ers prediction
NBA · Thursday, October 22, 2026 · 7:00 PM ET · Xfinity Mobile Arena · ESPN
Result
Final: Cleveland Cavaliers 106, Philadelphia 76ers 114 (Philadelphia 76ers won). Mel’s pick (Philadelphia 76ers win 62% of the time) was right. Against the spread, Mel’s lean was right. On the total, Mel’s lean was right.
Mel’s pick
Philadelphia 76ers win 62% of the time in Mel’s Playbook’s default simulation of this game, saved before it started.
- Cleveland Cavaliers: 38%
- Philadelphia 76ers: 62%
Projected score
Cleveland Cavaliers 107, Philadelphia 76ers 122. 5% of the simulations finished as one-score games.
Mel vs the betting line
Vegas has Philadelphia 76ers −3.5. Mel projects Philadelphia 76ers by 14.5, so the simulation leans Philadelphia 76ers -3.5 against the spread.
The total is 235.5; Mel projects 229.3 points, a lean to the under.
Recent form
Cleveland Cavaliers (0-0) scored 116 and allowed 120.3 points a game over their last 3.
Philadelphia 76ers (1-0) scored 112 and allowed 116 points a game over their last 5.
Based on this season’s stats, injuries, rest, travel and the betting market. Updated Oct 22, 9:11 AM ET.
See the full simulation
Mel’s Playbook Pro shows the range of likely totals and margins, player props and every factor behind the pick, and lets you tune the model (home field, injuries, momentum and more) and re-run the game.
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Every default-model prediction is saved before the game and graded against the final score on our public results page. Simulations are estimates, not guarantees, and this is not betting advice. 21+ where applicable; if gambling is a problem, call 1-800-GAMBLER.