Indianapolis Colts vs Jacksonville Jaguars prediction
NFL · Sunday, November 1, 2026 · 1:00 PM ET · EverBank Stadium · CBS
Mel’s pick
Jacksonville Jaguars win 63% of the time in Mel’s Playbook’s default simulation of this game.
- Indianapolis Colts: 37%
- Jacksonville Jaguars: 63%
Projected score
Indianapolis Colts 20, Jacksonville Jaguars 25. 18% of the simulations finished as one-score games.
Mel vs the betting line
Vegas has Jacksonville Jaguars −10. Mel projects Jacksonville Jaguars by 5.5, so the simulation leans Indianapolis Colts +10 against the spread.
The total is 46.5; Mel projects 45 points, a lean to the under.
Recent form
Indianapolis Colts (2-5) scored 20.2 and allowed 21.2 points a game over their last 5.
Jacksonville Jaguars (4-2) scored 24 and allowed 18.8 points a game over their last 5.
Based on this season’s stats, injuries, rest, travel, weather and the betting market. Updated Nov 1, 11:25 AM ET.
See the full simulation
Mel’s Playbook Pro shows the range of likely totals and margins, player props and every factor behind the pick, and lets you tune the model (home field, injuries, momentum and more) and re-run the game.
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Every default-model prediction is saved before the game and graded against the final score on our public results page. Simulations are estimates, not guarantees, and this is not betting advice. 21+ where applicable; if gambling is a problem, call 1-800-GAMBLER.